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Alterations of the gut microbiome and metabolic profile in CVB3-induced mice acute viral myocarditis

18 May 2023

Abstract excerpt

BACKGROUND: Acute viral myocarditis (AVMC) is an inflammatory disease of the myocardium. Evidence indicates that dysbiosis of gut microbiome and related metabolites intimately associated with cardiovascular diseases through the gut-heart axis. METHODS: We built mouse models of AVMC, then applied 16 S rDNA gene sequencing and UPLC-MS/MS metabolomics to explore variations of gut microbiome and disturbances of...

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PMID: 37202726
DOI: 10.1186/s12866-023-02863-4

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