Article
Immunoinformatic screening of Marburgvirus epitopes and computational investigations of epitope-allele complexes.
International immunopharmacology - 1 Oct 2022
Baral Prabin, Pavadai Elumalai, Zhou Ziyou, Xu Yang, Tison Christopher K, Pokhrel Rudramani, Gerstman Bernard S, Chapagain Prem P
Abstract excerpt
Marburgvirus (MARV), a member of the Filovirus family, causes severe hemorrhagic fever in humans. Currently, there are no approved vaccines or post exposure treatment methods available against MARV. With the aim of identifying vaccine candidates against MARV, we employ different sequence-based computational methods to predict the MHC-I and MHC-II T-cell epitopes as well as B-cell epitopes for the complete MARV...
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