Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

IPO7 Promotes Odontoblastic Differentiation and Inhibits Osteoblastic Differentiation Through Regulation of RUNX2 Expression and Translocation

3 Aug 2022

Abstract excerpt

RUNX2, an important transcriptional factor for both odontoblastic and osteoblastic differentiation, is upregulated during osteoblastic differentiation, but downregulated during late odontoblastic differentiation. However, the specific mechanism of the different RUNX2 expression in bone and dentin remains largely unknown. Importin 7 (IPO7), a member of the karyopherin β-superfamily, mediates nucleocytoplasmic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bone Metabolism and Diseases
Share to Neurogenetic and Muscular Disorders Research
Share to Oral and gingival health research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 35922041
DOI: 10.1093/stmcls/sxac055

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

IPO7 Promotes Odontoblastic Differentiation and Inhibits Osteoblastic Differentiation Through Regulation of RUNX2 Expression and TranslocationPMID 35922041Read ↗

<i>Runx2, Osx</i> , and <i>Dspp</i> in Tooth DevelopmentSemantic proximity Read ↗

Non-coding RNAs repressive role in post-transcriptional processing of RUNX2 during the acquisition of the osteogenic phenotype of periodontal ligament mesenchymal stem cells.Semantic proximity Read ↗

HDAC6 regulates dental mesenchymal stem cells and osteoclast differentiationSemantic proximity Read ↗

miR-675 promotes odontogenic differentiation of human dental pulp cells by epigenetic regulation of DLX3Semantic proximity Read ↗

Mechanisms during Osteogenic Differentiation in Human Dental Follicle CellsSemantic proximity Read ↗

Differential expression of long noncoding RNAs in SDF-1α-induced odontogenic differentiation of human dental pulp stem cellsSemantic proximity Read ↗

Elucidating epigenetic mechanisms governing odontogenic differentiation in dental pulp stem cells: an in-depth explorationSemantic proximity Read ↗

Optineurin Cooperates With NRF2 to Regulate Tooth Root Morphogenesis by Controlling Mitochondrial Dynamics and ApoptosisSemantic proximity Read ↗

CKIP-1 suppresses odontoblastic differentiation of dental pulp stem cells via BMP2 pathway and can interact with NRP1.Semantic proximity Read ↗

MiR-497-5p Regulates Osteo/Odontogenic Differentiation of Stem Cells From Apical Papilla via the Smad Signaling Pathway by Targeting Smurf2Semantic proximity Read ↗

Lineage-specific exosomes promote the odontogenic differentiation of human dental pulp stem cells (DPSCs) through TGFβ1/smads signaling pathway via transfer of microRNAsSemantic proximity Read ↗

The Proneural Transcription Factor Atoh1 Promotes Odontogenic/Osteogenic Differentiation in Human Dental Pulp Stem Cells (DPSCs)Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.