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Article

CKIP-1 suppresses odontoblastic differentiation of dental pulp stem cells via BMP2 pathway and can interact with NRP1.

Connective tissue research - 1 Mar 2019

Song Yihua, Wang Chenfei, Gu Zhifeng, Cao Peipei, Huang Dan, Feng Guijuan, Lian Min, Zhang Ye, Feng Xingmei, Gao Zhenran

Abstract excerpt

AIM: Casein kinase 2 interacting protein-1 (CKIP-1) is a recently discovered intracellular regulator of bone formation, muscle cell differentiation, and tumor cell proliferation. Our study aims to identify the inhibition of BMP2-Smad1/5 signaling by CKIP-1 in odontoblastic differentiation of human dental pulp stem cells (DPSCs). MATERIALS AND METHODS: DPSCs infected CKIP-1 siRNA or transfected CKIP-1 full-length...

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Source

Identifiers

PMID: 29852799
DOI: 10.1080/03008207.2018.1483355

Genes

BMP2
NRP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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