Article
Identification of a novel mutation involved in colistin resistance in Klebsiella pneumoniae through Next-Generation Sequencing (NGS) based approaches.
The new microbiologica - 1 Jul 2022
Sisti Sofia, Diotti Roberta A., Caputo Valeria, Libera Martina, Ferrarese Roberto, Carletti Silvia, Rizzi Pierfrancesco, Cirillo Daniela Maria, Lorenzin Giovanni, Clementi Massimo, Mancini Nicasio, Clementi Nicola
Abstract excerpt
The spread of multidrug-resistant (MDR) K. pneumoniae carbapenemase-producing bacteria (KPC) is one of the most serious threats to global public health. Due to the limited antibiotic options, colis- tin often represents a therapeutic choice. In this study, we performed Whole-Genome Sequencing (WGS) by Illumina and Nanopore platforms on four colistin-resistant K. pneumoniae isolates (CoRKp) to explore the...
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