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The role of genetic risk factors of Alzheimer's disease in synaptic dysfunction

30 Jul 2022

Abstract excerpt

Alzheimer's disease (AD) is a neurodegenerative disease characterized by the progressive deterioration of cognitive functions. Due to the extended global life expectancy, the prevalence of AD is increasing among aging populations worldwide. While AD is a multifactorial disease, synaptic dysfunction is one of the major neuropathological changes that occur early in AD, before clinical symptoms appear, and is...

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PMID: 35918217
DOI: 10.1016/j.semcdb.2022.07.011

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