Article
The -α3.7III subtype of α+-thalassemia was identified in China.
Hematology (Amsterdam, Netherlands) - 1 Dec 2022
Bao Xiuqin, Wang Jicheng, Qin Danqing, Zhang Rui, Yao Cuize, Liang Jie, Liang Kailing, Du Li
Abstract excerpt
OBJECTIVE: The 3.7 kb deletion (-α3.7) in the α-globin cluster, which characterizes α+-thalassemia, has been reported to have a carrier rate of 4.78% in southern China. Three -α3.7 subtypes have been identified worldwide. However, the -α3.7 III subtype has not previously been identified in China. Herein, we reported identification of the -α3.7 III subtype in a Chinese patient. METHODS: We used gap-PCR and a...
Topics
- China
- Female
- Genotype
- Heterozygote
- Humans
- Pregnancy
- alpha-Globins
- alpha-Thalassemia