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Article

Impact of BRCA1/2 cascade testing on anxiety, depression, and cancer worry levels among unaffected relatives in a multiethnic Asian cohort.

Journal of genetic counseling - 1 Feb 2023

Padmanabhan Heamanthaa, Mariapun Shivaani, Lee Sheau-Yee, Hassan Nur Tiara, Lee Daphne Shin-Chi, Meiser Bettina, Wong Siu-Wan, Lee Yong-Quan, Yip Cheng-Har, Teo Soo-Hwang, Thong Meow-Keong, Taib Nur Aishah Mohd, Yoon Sook-Yee

Abstract excerpt

Cascade testing for families with BRCA pathogenic variants is important to identify relatives who are carriers. These relatives can benefit from appropriate risk management and preventative strategies arising from an inherited increased risk of breast, ovarian, prostate, melanoma, and pancreatic cancers. Cascade testing has the potential to enable cost-effective cancer control even in low- and middle-income...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 35913122
DOI: 10.1002/jgc4.1619

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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