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Potential predictive value of comutant LRP1B and FAT for immune response in non-small cell lung cancer

26 Jul 2022

Abstract excerpt

BACKGROUND: Preliminary investigation revealed that Low-density lipoprotein receptor-related protein 1b (LRP1B) and FAT atypical cadherin (FAT) family mutation might serve as immune regulators under certain tumor microenvironment. EXPERIMENTAL DESIGN: We curated a total of 70 non-small cell lung cancer (NSCLC) patients who harbored alterations in LRP1B and/or FAT family (FAT1/2/3/4) based on next-generation...

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PMID: 35905642
DOI: 10.1016/j.tranon.2022.101493

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