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Article

Sex-Dependent Mediation of Leptin in the Association of Perilipin Polymorphisms with BMI and Plasma Lipid Levels in Children.

Nutrients - 26 Jul 2022

Vales-Villamarín Claudia, Lumpuy-Castillo Jairo, Gavela-Pérez Teresa, de Dios Olaya, Pérez-Nadador Iris, Soriano-Guillén Leandro, Garcés Carmen

Abstract excerpt

Variations in the perilipin (PLIN) gene have been suggested to be associated with obesity and its related alterations, but a different nutritional status seems to contribute to differences in these associations. In our study, we examined the association of several polymorphisms at the PLIN locus with obesity and lipid profile in children, and then analyzed the mediation of plasma leptin levels on these...

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Identifiers

PMID: 35893926
DOI: 10.3390/nu14153072
PMCID: PMC9332311

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