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Therapeutic Potential of Intrabodies for Cancer Immunotherapy: Current Status and Future Directions

18 Jul 2022

Abstract excerpt

Tumor cells are characterized by overexpressed tumor-associated antigens or mutated neoantigens, which are expressed on the cell surface or intracellularly. One strategy of cancer immunotherapy is to target cell-surface-expressed tumor-associated antigens (TAAs) with therapeutic antibodies. For targeting TAAs or neoantigens, adoptive T-cell therapies with activated autologous T cells from cancer patients...

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PMID: 35892709
DOI: 10.3390/antib11030049

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