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Article

Population replacement gene drive characteristics for malaria elimination in a range of seasonal transmission settings: a modelling study

26 Jul 2022

Abstract excerpt

BACKGROUND: Gene drives are a genetic engineering method where a suite of genes is inherited at higher than Mendelian rates and has been proposed as a promising new vector control strategy to reinvigorate the fight against malaria in sub-Saharan Africa. METHODS: Using an agent-based model of malaria transmission with vector genetics, the impacts of releasing population-replacement gene drive mosquitoes on malaria...

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PMID: 35883100
DOI: 10.1186/s12936-022-04242-2

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