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Article

Genetic variations in GABA metabolism and epilepsy.

Seizure - 1 Oct 2022

Feng Yan, Wei Zi-Han, Liu Chao, Li Guo-Yan, Qiao Xiao-Zhi, Gan Ya-Jing, Zhang Chu-Chu, Deng Yan-Chun

Abstract excerpt

Epilepsy is a paroxysmal brain disorder that results from an imbalance between neuronal excitation and inhibition. Gamma-aminobutyric acid (GABA) is the most important inhibitory neurotransmitter in the brain and plays an important role in the occurrence and development of epilepsy. Abnormalities in all aspects of GABA metabolism, including GABA synthesis, transport, genes encoding GABA receptors, and GABA...

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Identifiers

PMID: 35850019
DOI: 10.1016/j.seizure.2022.07.007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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