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Droplet digital PCR for genetic mutations monitoring predicts relapse risk in pediatric acute myeloid leukemia.

International journal of hematology - 1 Nov 2022

Chen Xiaoyan, Liu Lipeng, Zhang Aoli, Yi Meihui, Lan Yang, Zheng Zhongzheng, Zhang Luyang, Liu Xiaoming, Chang Lixian, Zou Yao, Ruan Min, Zhu Xiaofan

Abstract excerpt

Multiparameter flow cytometry (MFC)-based minimal residual disease has been a poor predictor of prognosis in children with acute myeloid leukemia (AML). This study aimed to evaluate the incremental value of serial monitoring by droplet digital PCR (ddPCR) in forecasting the outcome of AML. Twenty-four children with AML were enrolled and the relapse-free survival (RFS) rate was estimated using the Kaplan-Meier...

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Acute Myeloid Leukemia Research
Cancer Genomics and Diagnostics
Child
Leukemia, Myeloid, Acute
Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Neoplasm, Residual

Polymerase Chain Reaction

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PMID: 35849248
DOI: 10.1007/s12185-022-03402-z

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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