Article
Lack of Association of Polymorphisms in IL22 and IL22RA1 Genes with Fibrosis Severity in Patients with Chronic Hepatitis C.
Viral immunology - 1 Sept 2022
de Brito Rodrigo José Videres Cordeiro, do Carmo Rodrigo Feliciano, Silva Bruna Manuella Souza, Barbosa Júnior Walter Lins, Vasconcelos Luydson Richardson Silva, Pereira Leila Maria Moreira Beltrão, Moura Patrícia
Abstract excerpt
The IL-22 pathway has been shown to play an important role in the pathogenesis of liver fibrosis. However, little is known about the role of single-nucleotide polymorphisms (SNPs) in IL-22-related genes in relation to the severity of liver fibrosis. This study aimed to investigate the association of polymorphisms in IL22 and IL22RA1 genes with the severity of liver fibrosis in patients with chronic hepatitis C. A...
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