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Oxidative Stress Causes Masculinization of Genetically Female Medaka Without Elevating Cortisol

16 Jun 2022

Abstract excerpt

Medaka (Oryzias latipes) is a teleost fish with an XX/XY sex determination system. Sex reversal from female-to-male (masculinization of XX fish) can be induced through cortisol elevation from exposure to environmental stress such as high temperature during sexual differentiation. However, the effects of oxidative stress, generated via metabolic reactions and biological defense mechanisms, on the sexual...

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PMID: 35832427
DOI: 10.3389/fendo.2022.878286

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