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TRAF3IP3 Is Cleaved by EV71 3C Protease and Exhibits Antiviral Activity

23 Jun 2022

Abstract excerpt

Enterovirus 71 (EV71) is one of the major pathogens of hand, foot, and mouth disease, which poses a major risk to public health and infant safety. 3C protease (3Cpro), a non-structural protein of EV71, promotes viral protein maturation by cleaving polyprotein precursors and facilitates viral immune escape by cleaving host proteins. In this study, we screened for human proteins that could interact with EV71 3Cpro...

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PMID: 35814660
DOI: 10.3389/fmicb.2022.914971

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