Influence of polymorphisms on the phenotype of TLR1, TLR4 and TLR9 genes and their association with cervical cancer: Bioinformatics prediction analysis and a case-control study.

doi:10.1016/j.cancergen.2024.10.001

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Article

Influence of polymorphisms on the phenotype of TLR1, TLR4 and TLR9 genes and their association with cervical cancer: Bioinformatics prediction analysis and a case-control study.

Cancer genetics - 1 Nov 2024

Moura Edilson Leite de, Santos Israel Faustino Dos, Freitas Paulo Pedro de, Silva Denise Macedo da, Santos Ana Caroline Melo Dos, Silva Aline Cristine Pereira E, Lira Neto Abel Barbosa, Barros Rubens Pessoa de, Neves Jhonatan David Santos das, Barbosa Nirliane Ribeiro, Marques Carolinne de Sales, Fraga Carlos Alberto de Carvalho, Farias Karol Fireman de, Figueiredo Elaine Virginia Martins de Souza

Abstract excerpt

Susceptibility to cervical cancer has been associated with Toll-like receptors (TLRs), which is an important component of innate immunity. According to previous studies, polymorphisms in TLRs genes can affect immune response pathways and lead to the development of cervical cancer. The present study aims to evaluate the functionality of polymorphisms in TLR1, TLR4 and TLR9 genes and their associations with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39418818
DOI: 10.1016/j.cancergen.2024.10.001

Genes

TLR1
TLR4
TLR9
THAP1

Variants

rs4986790

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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