Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A stable XPG protein is required for proper ribosome biogenesis: Insights on the phenotype of combinate Xeroderma Pigmentosum/Cockayne Syndrome patients.

PloS one - 1 Jan 2022

Taupelet Florent, Donnio Lise-Marie, Magnani Charlène, Mari Pierre-Olivier, Giglia-Mari Giuseppina

Abstract excerpt

Nucleotide Excision Repair is one of the five DNA repair systems. More than 30 proteins are involved in this process, including the seven XP proteins. When mutated, the genes coding for these proteins are provoking the rare disease Xeroderma Pigmentosum, which causes cutaneous defects and a high prevalence of skin cancers in patients. The CSA and CSB proteins are also involved in Nucleotide Excision Repair, and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cockayne Syndrome
Share to DNA, Ribosomal

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Endonucleases

Share to Rare Diseases

Share to Ribosomes

Share to RNA Precursors

Share to RNA, Ribosomal

Share to Xeroderma Pigmentosum

Source

Open in PubMed Open full text

Identifiers

PMID: 35802638
DOI: 10.1371/journal.pone.0271246
PMCID: PMC9269744

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A stable XPG protein is required for proper ribosome biogenesis: Insights on the phenotype of combinate Xeroderma Pigmentosum/Cockayne Syndrome patients.PMID 35802638Read ↗

Cockayne Syndrome-Associated CSA and CSB Mutations Impair Ribosome Biogenesis, Ribosomal Protein Stability, and Global Protein Folding.Semantic proximity Read ↗

Loss of Proteostasis Is a Pathomechanism in Cockayne Syndrome.Semantic proximity Read ↗

Overview of xeroderma pigmentosum proteins architecture, mutations and post-translational modifications.Semantic proximity Read ↗

Every protagonist has a sidekick: Structural aspects of human xeroderma pigmentosum-binding proteins in nucleotide excision repair.Semantic proximity Read ↗

Insufficiency of 40S ribosomal proteins, RPS26 and RPS25, negatively affects biosynthesis of polyglycine-containing proteins in fragile-X associated conditionsSemantic proximity Read ↗

The emerging role of Cockayne group A and B proteins in ubiquitin/proteasome-directed protein degradation.Semantic proximity Read ↗

Molecular etiology of defective nuclear and mitochondrial ribosome biogenesis: Clinical phenotypes and therapy.Semantic proximity Read ↗

Revisiting the structural features of the xeroderma pigmentosum proteins: Focus on mutations and knowledge gaps.Semantic proximity Read ↗

How Altered Ribosome Production Can Cause or Contribute to Human Disease: The Spectrum of Ribosomopathies.Semantic proximity Read ↗

Ribosomal proteins and human diseases: molecular mechanisms and targeted therapy.Semantic proximity Read ↗

The functions of RPS19 and their relationship to Diamond-Blackfan anemia: a review.Semantic proximity Read ↗

Eukaryotic ribosome quality control system: a potential therapeutic target for human diseasesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.