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Gut microbiota composition in colorectal cancer patients is genetically regulated

6 Jul 2022

Abstract excerpt

The risk of colorectal cancer (CRC) depends on environmental and genetic factors. Among environmental factors, an imbalance in the gut microbiota can increase CRC risk. Also, microbiota is influenced by host genetics. However, it is not known if germline variants influence CRC development by modulating microbiota composition. We investigated germline variants associated with the abundance of bacterial populations...

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PMID: 35794137
DOI: 10.1038/s41598-022-15230-6

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