Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

SARS-CoV-2 fusion-inhibitory lipopeptides maintain high potency against divergent variants of concern including Omicron

4 Jul 2022

Abstract excerpt

The emergence of SARS-CoV-2 Omicron and other variants of concern (VOCs) has brought huge challenges to control the COVID-19 pandemic, calling for urgent development of effective vaccines and therapeutic drugs. In this study, we focused on characterizing the impacts of divergent VOCs on the antiviral activity of lipopeptide-based fusion inhibitors that we previously developed. First, we found that pseudoviruses...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to COVID-19 Clinical Research Studies
Share to SARS-CoV-2 and COVID-19 Research
Share to Viral gastroenteritis research and epidemiology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 35786417
DOI: 10.1080/22221751.2022.2098060

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

SARS-CoV-2 fusion-inhibitory lipopeptides maintain high potency against divergent variants of concern including OmicronPMID 35786417Read ↗

Nanomolar anti-SARS-CoV-2 Omicron activity of the host-directed TMPRSS2 inhibitor N-0385 and synergistic action with direct-acting antiviralsSemantic proximity Read ↗

A Detailed Overview of SARS-CoV-2 Omicron: Its Sub-Variants, Mutations and Pathophysiology, Clinical Characteristics, Immunological Landscape, Immune Escape, and Therapies.Semantic proximity Read ↗

Evolutionary characteristics of SARS-CoV-2 Omicron subvariants adapted to the hostSemantic proximity Read ↗

Design and characterization of novel SARS-CoV-2 fusion inhibitors with N-terminally extended HR2 peptidesSemantic proximity Read ↗

SARS-CoV-2 Omicron Variant Spike Glycoprotein Mutation Q954H Enhances Fusion Core Stability.Semantic proximity Read ↗

Intrinsic D614G and P681R/H mutations in SARS-CoV-2 VoCs Alpha, Delta, Omicron and viruses with D614G plus key signature mutations in spike protein alters fusogenicity and infectivity.Semantic proximity Read ↗

A trifunctional peptide broadly inhibits SARS-CoV-2 Delta and Omicron variants in hamstersSemantic proximity Read ↗

SARS-CoV-2 Omicron Specific Mutations Affecting Infectivity, Fusogenicity, and Partial TMPRSS2-Independency.Semantic proximity Read ↗

The impact of S2 mutations on Omicron SARS-CoV-2 cell surface expression and fusogenicity.Semantic proximity Read ↗

SARS-CoV-2 spike S375F mutation characterizes the Omicron BA.1 variantSemantic proximity Read ↗

Developing Pseudovirus-Based Neutralization Assay against Omicron-Included SARS-CoV-2 VariantsSemantic proximity Read ↗

A stapled lipopeptide platform for preventing and treating highly pathogenic viruses of pandemic potentialSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.