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Article

Patient with multiple genetically distinct thyroid nodules including papillary thyroid carcinoma harboring novel YWHAG-BRAF fusion.

Cancer genetics - 1 Aug 2022

Lin Ruihe, Wang Zi-Xuan, Cottrill Elizabeth, Badjatia Nitika, Gargano Stacey M

Abstract excerpt

Next-generation sequencing (NGS) analysis of thyroid samples aids in risk stratification of cytologically indeterminate nodules and contributes to our understanding of molecular mechanisms in thyroid neoplasia. Several genes, including BRAF, RAS, and EIF1AX, are known to play a role in thyroid tumorigenesis. Here we report a case of papillary thyroid carcinoma (PTC) in which a single lesion harbored a novel...

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PMID: 35780657
DOI: 10.1016/j.cancergen.2022.06.006

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