Article
Heme oxygenase-1 gene rs2071746 polymorphism in retinal vein occlusion.
Ophthalmic genetics - 1 Oct 2022
Posch-Pertl Laura, List Wolfgang, Michelitsch Monja, Pinter-Hausberger Silke, Berisha Bujar, Posch Florian, Kloeckl Lorenz, Renner Wilfried, Weger Martin
Abstract excerpt
BACKGROUND: Heme oxygenase-1 (HO-1) is an important cytoprotective enzyme due to its ability to degrade pro-inflammatory heme. The common single nucleotide polymorphism (SNP) rs2071746 on the HMOX1 gene has been associated with HO-1 activity and a variety of cardiovascular diseases. This study was performed to investigate the association between the rs2071746 SNP and retinal vein occlusion (RVO). METHODS: We...
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