Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Modeling tuberous sclerosis complex with human induced pluripotent stem cells.

World journal of pediatrics : WJP - 1 Mar 2024

Niu Weibo, Siciliano Benjamin, Wen Zhexing

Abstract excerpt

BACKGROUND: Tuberous sclerosis complex (TSC) is an autosomal dominant genetic disorder with a birth incidence of 1:6000 in the United States that is characterized by the growth of non-cancerous tumors in multiple organ systems including the brain, kidneys, lungs, and skin. Importantly, TSC is also associated with significant neurological manifestations including epilepsy, TSC-associated neuropsychiatric...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autism Spectrum Disorder
Share to Induced Pluripotent Stem Cells
Share to Mammals

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mutation

Share to Signal Transduction

Share to Tuberous Sclerosis

Source

Identifiers

PMID: 35759110
DOI: 10.1007/s12519-022-00576-8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Modeling tuberous sclerosis complex with human induced pluripotent stem cells.PMID 35759110Read ↗

Recent advances in human stem cell-based modeling of Tuberous Sclerosis ComplexSemantic proximity Read ↗

Establishment of human induced pluripotent stem cell lines, KMUGMCi006, from a patient with Tuberous sclerosis complex (TSC) bearing mosaic nonsense mutations in the Tuberous sclerosis complex 2 (TSC2) gene.Semantic proximity Read ↗

Modeling Rett Syndrome with Human Pluripotent Stem Cells: Mechanistic Outcomes and Future Clinical Perspectives.Semantic proximity Read ↗

Advances and Current Challenges Associated with the Use of Human Induced Pluripotent Stem Cells in Modeling Neurodegenerative DiseaseSemantic proximity Read ↗

Human Induced Pluripotent Stem Cells : Clinical Significance and Applications in Neurologic DiseasesSemantic proximity Read ↗

Disease-Specific iPS Cell Models in NeuroscienceSemantic proximity Read ↗

Induced pluripotent stem cells for modelling human diseasesSemantic proximity Read ↗

Heterozygous loss of TSC2 alters p53 signaling and human stem cell reprogramming.Semantic proximity Read ↗

In-a-dish: induced pluripotent stem cells as a novel model for human diseases.Semantic proximity Read ↗

Establishment of Tsc2‑deficient rat embryonic stem cells.Semantic proximity Read ↗

Longitudinal multi-omics reveals pathogenic <i>TSC2</i> variants disrupt developmental trajectories of human cortical organoids derived from Tuberous Sclerosis ComplexSemantic proximity Read ↗

The translational potential of human induced pluripotent stem cells for clinical neurology : The translational potential of hiPSCs in neurology.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.