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Article

Transforming Growth Factor Beta Receptor 2 (TGFBR2) Promoter Region Polymorphisms May Be Involved in Mandibular Retrognathism.

BioMed research international - 1 Jan 2022

Kirschneck Margarita, Zbidat Nermien, Paddenberg Eva, Reis Caio Luiz Bitencourt, Madalena Isabela Ribeiro, de Menezes-Oliveira Maria Angélica Hueb, Lepri César Penazzo, Proff Peter, Kirschneck Christian, Küchler Erika Calvano

Abstract excerpt

Skeletal malocclusions are common phenotypes in humans and have a strong influence on genetic factors. Transforming growth factor beta (TGFβ) controls numerous functions of the human body, including cell proliferation, differentiation, and migration. Thus, this study is aimed at evaluating whether genetic polymorphisms in TGFB1 and its receptor TGFBR2 are associated with mandibular retrognathism in German...

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Adolescent
Connective tissue disorders research
dental development and anomalies
Malocclusion

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Single Nucleotide

Promoter Regions, Genetic

Receptor, Transforming Growth Factor-beta Type II

Transforming Growth Factor beta1

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Identifiers

PMID: 35757474
DOI: 10.1155/2022/1503052
PMCID: PMC9217526

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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