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Article

Variants Near NOG and SOX9 Are Associated with Mandibular Retrognathia.

Journal of dental research - 1 Jul 2026

Juuri E, Strausz S, Hasan Md R, Hongqiang M, Jónsson T, Thordarsson Á, Auðólfsson G, Gudbjartsson D, Stefansson H, Nieminen P, Ollila H M, Rice D P

Abstract excerpt

Mandibular retrognathia is a common craniofacial anomaly characterized by a posteriorly positioned mandible, which can affect a person's oral function, esthetics, and quality of life. While facial characteristics are widely acknowledged to have a hereditary component, the etiology of this skeletal anomaly is poorly understood. This study aims to identify genetic loci associated with mandibular retrognathia and...

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Carrier Proteins
Cohort Studies
Enhancer Elements, Genetic
Finland
Iceland

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Linkage Disequilibrium

SOX9 Transcription Factor

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Open in PubMed Open full text

Identifiers

PMID: 41408424
DOI: 10.1177/00220345251397375
PMCID: PMC13312417

Genes

SOX9
NOG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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