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Article

Singular Interface Dynamics of the SARS-CoV-2 Delta Variant Explained with Contact Perturbation Analysis.

Journal of chemical information and modeling - 27 Jun 2022

Gheeraert Aria, Vuillon Laurent, Chaloin Laurent, Moncorgé Olivier, Very Thibaut, Perez Serge, Leroux Vincent, Chauvot de Beauchêne Isaure, Mias-Lucquin Dominique, Devignes Marie-Dominique, Rivalta Ivan, Maigret Bernard

Abstract excerpt

Emerging SARS-CoV-2 variants raise concerns about our ability to withstand the Covid-19 pandemic, and therefore, understanding mechanistic differences of those variants is crucial. In this study, we investigate disparities between the SARS-CoV-2 wild type and five variants that emerged in late 2020, focusing on the structure and dynamics of the spike protein interface with the human angiotensin-converting enzyme...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 35754360
DOI: 10.1021/acs.jcim.2c00350
PMCID: PMC9199437

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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