Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Dysregulation of the Enteric Nervous System in the Mid Colon of Complement Component 3 Knockout Mice with Constipation Phenotypes.

International journal of molecular sciences - 20 Jun 2022

Choi Yun Ju, Song Hee Jin, Kim Ji Eun, Lee Su Jin, Jin You Jeong, Roh Yu Jeong, Seol Ayun, Kim Hye Sung, Hwang Dae Youn

Abstract excerpt

Complement component 3 (C3) contributes to neurogenesis, neural migration, and synaptic elimination under normal and disease conditions of the brain, even though it has not been studied in the enteric nervous system (ENS). To determine the role of C3 in the regulatory mechanism of ENS during C3 deficiency-induced constipation, the changes in the markers of neuronal and interstitial cells of Cajal (ICCs), the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Colon
Share to Complement C3

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Constipation

Share to Enteric Nervous System

Share to Mice, Knockout

Share to Phenotype

Share to Serotonin

Source

Open in PubMed Open full text

Identifiers

PMID: 35743302
DOI: 10.3390/ijms23126862
PMCID: PMC9225043

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Dysregulation of the Enteric Nervous System in the Mid Colon of Complement Component 3 Knockout Mice with Constipation Phenotypes.PMID 35743302Read ↗

Similarities and differences in constipation phenotypes between Lep knockout mice and high fat diet-induced obesity mice.Semantic proximity Read ↗

Enteric nervous system degeneration in human and murine CLN3 disease, is ameliorated by gene therapy in miceSemantic proximity Read ↗

The Enteric Nervous System and Its Emerging Role as A Therapeutic TargetSemantic proximity Read ↗

Building a second brain in the bowelSemantic proximity Read ↗

Caecal dysfunction in the NL3 <sup>R451C</sup> mouse model of autismSemantic proximity Read ↗

Abnormal enteric nervous system and motor activity in the ganglionic proximal bowel of Hirschsprung’s diseaseSemantic proximity Read ↗

Involvement of Enteric Glia in Small Intestine Neuromuscular Dysfunction of Toll-Like Receptor 4-Deficient Mice.Semantic proximity Read ↗

Gut feelings: Studying enteric nervous system development, function, and disease in the zebrafish model systemSemantic proximity Read ↗

Novel understanding on genetic mechanisms of enteric neuropathies leading to severe gut dysmotility.Semantic proximity Read ↗

Impaired cecal motility and secretion alongside expansion of gut-associated lymphoid tissue in the Nlgn3R451C mouse model of autismSemantic proximity Read ↗

The zebrafish mutant lessen: an experimental model for congenital enteric neuropathies.Semantic proximity Read ↗

Zebrafish: A Model Organism for Studying Enteric Nervous System Development and DiseaseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.