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Diagnostic classification of cancers using DNA methylation of paracancerous tissues

23 Jun 2022

Abstract excerpt

The potential role of DNA methylation from paracancerous tissues in cancer diagnosis has not been explored until now. In this study, we built classification models using well-known machine learning models based on DNA methylation profiles of paracancerous tissues. We evaluated our methods on nine cancer datasets collected from The Cancer Genome Atlas (TCGA) and utilized fivefold cross-validation to assess the...

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PMID: 35739223
DOI: 10.1038/s41598-022-14786-7

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