Article
Comprehensive Viral Genotyping Reveals Prognostic Viral Phylogenetic Groups in HPV16-Associated Squamous Cell Carcinoma of the Oropharynx.
Molecular cancer research : MCR - 4 Oct 2022
Schrank Travis P, Landess Lee, Stepp Wesley H, Rehmani Hina, Weir William H, Lenze Nicholas, Lal Asim, Wu Di, Kothari Aditi, Hackman Trevor G, Sheth Siddharth, Patel Shetal, Jefferys Stuart R, Issaeva Natalia, Yarbrough Wendell G
Abstract excerpt
Human papillomavirus-positive (HPV+) squamous cell carcinoma of the oropharynx (OPSCC) is the most prevalent HPV-associated malignancy in the United States and is primarily caused by HPV subtype 16 (HPV16). Favorable treatment outcomes have led to increasing interest in treatment deescalation to reduce treatment-related morbidity. Prognostic biomarkers are needed to identify appropriately low-risk patients for...
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