Multicenter Evaluation of the Idylla GeneFusion in Non-Small-Cell Lung Cancer.

doi:10.1016/j.jmoldx.2022.05.004

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Article

Multicenter Evaluation of the Idylla GeneFusion in Non-Small-Cell Lung Cancer.

The Journal of molecular diagnostics : JMD - 1 Sept 2022

Depoilly Thomas, Garinet Simon, van Kempen Léon C, Schuuring Ed, Clavé Sergi, Bellosillo Beatriz, Ercolani Cristiana, Buglioni Simonetta, Siemanowski Janna, Merkelbach-Bruse Sabine, Tischler Verena, Demes Melanie-Christin, Paridaens Henry, Sibille Catherine, de Montpreville Vincent Thomas, Rouleau Etienne, Bartczak Artur, Pasieka-Lis Monika, Teo Ryan Yee Wei, Chuah Khoon Leong, Barbosa Marta, Quintana Carlos, Biscuola Michele, Delgado-Garcia Mercedes, Vacirca Davide, Rappa Alessandra, Cashmore Matthew, Smith Matthew, Jasionowicz Piotr, Meeney Adam, Desmeules Patrice, Terris Benoit, Mansuet-Lupo Audrey

Abstract excerpt

Targeted therapy in lung cancer requires the assessment of multiple oncogenic driver alterations, including fusion genes. This retrospective study evaluated the Idylla GeneFusion prototype, an automated and ease-of-use (<2 minutes) test, with a short turnaround time (3 hours) to detect fusions involving ALK, ROS1, RET, and NTRK1/2/3 genes and MET exon 14 skipping. This multicenter study (18 centers) included 313...

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PMID: 35718095
DOI: 10.1016/j.jmoldx.2022.05.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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