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Identifying alcohol misuse biotypes from neural connectivity markers and concurrent genetic associations

16 Jun 2022

Abstract excerpt

Alcohol use behaviors are highly heterogeneous, posing significant challenges to etiologic research of alcohol use disorder (AUD). Magnetic resonance imaging (MRI) provides intermediate endophenotypes in characterizing problem alcohol use and assessing the genetic architecture of addictive behavior. We used connectivity features derived from resting state functional MRI to subtype alcohol misuse (AM) behavior....

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PMID: 35710901
DOI: 10.1038/s41398-022-01983-1

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