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Article

Data-Driven Phenotypic Categorization for Neurobiological Analyses: Beyond DSM-5 Labels.

Biological psychiatry - 15 Mar 2017

Van Dam Nicholas T, O'Connor David, Marcelle Enitan T, Ho Erica J, Cameron Craddock R, Tobe Russell H, Gabbay Vilma, Hudziak James J, Xavier Castellanos F, Leventhal Bennett L, Milham Michael P

Abstract excerpt

BACKGROUND: Data-driven approaches can capture behavioral and biological variation currently unaccounted for by contemporary diagnostic categories, thereby enhancing the ability of neurobiological studies to characterize brain-behavior relationships. METHODS: A community-ascertained sample of individuals (N = 347, 18-59 years of age) completed a battery of behavioral measures, psychiatric assessment, and...

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Identifiers

PMID: 27667698
DOI: 10.1016/j.biopsych.2016.06.027
PMCID: PMC5402759

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