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Identification of MYH9 Key Domain Involved in the Entry of PRRSV Into Permissive Cells

25 May 2022

Abstract excerpt

Porcine reproductive and respiratory syndrome virus (PRRSV) is an important pathogen that causes huge losses economically to the pig industry worldwide. Previous research suggested that receptor dependence is necessary for PRRSV infection. MYH9 and CD163 are indispensable for PRRSV entry into a porcine alveolar macrophage. In the present study, human MYH9 (hMYH9) and mouse MYH9 (mMYH9), similar to swine MYH9,...

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PMID: 35694306
DOI: 10.3389/fmicb.2022.865343

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