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Purification of human iPSC-derived cells at large scale using microRNA switch and magnetic-activated cell sorting

9 Jun 2022

Abstract excerpt

For regenerative cell therapies using pluripotent stem cell (PSC)-derived cells, large quantities of purified cells are required. Magnetic-activated cell sorting (MACS) is a powerful approach to collect target antigen-positive cells; however, it remains a challenge to purify various cell types efficiently at large scale without using antibodies specific to the desired cell type. Here we develop a technology that...

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PMID: 35688152
DOI: 10.1016/j.stemcr.2022.05.003

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