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Article

Magselectofection: an integrated method of nanomagnetic separation and genetic modification of target cells

1 Mar 2011

Abstract excerpt

Research applications and cell therapies involving genetically modified cells require reliable, standardized, and cost-effective methods for cell manipulation. We report a novel nanomagnetic method for integrated cell separation and gene delivery. Gene vectors associated with magnetic nanoparticles are used to transfect/transduce target cells while being passaged and separated through a high gradient magnetic...

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PMID: 21357765
DOI: 10.1182/blood-2010-08-302646

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