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Article

THSD7B Mutation Induces Platinum Resistance in Small Cell Lung Cancer Patients.

Drug design, development and therapy - 1 Jan 2022

Yao Zifu, Lin Anqi, Yi Yonglin, Shen Weitao, Zhang Jian, Luo Peng

Abstract excerpt

Aim: Several cases of small cell lung cancer (SCLC) patients demonstrate resistance to the treatment initiatives such as cisplatin after platinum chemotherapy. It is crucial to the improvement of the overall survival (OS) of SCLC patients to discover the gene mutation inducing platinum resistance within this cohort. Patients and Methods: We analyzed the gene mutations significantly associated with the OS from 2...

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Identifiers

PMID: 35685767
DOI: 10.2147/DDDT.S363665
PMCID: PMC9172928

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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