Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Targeting m6A modification inhibits herpes virus 1 infection

22 Feb 2021

Abstract excerpt

The latent infection by herpes virus type 1 (HSV-1) may be lifelong in trigeminal ganglia and a suspected cause of Alzheimer's Disease (AD) and Amyotrophic lateral sclerosis (ALS). Whether and how N6-methyladenosine (m6A) modification of viral RNAs affects virus infection are poorly understood. Here, we report that HSV-1 infection enhanced the expression of m6A writers (METTL3, METTL14) and readers (YTHDF1/2/3)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to RNA modifications and cancer
Share to Viral-associated cancers and disorders

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 35685469
DOI: 10.1016/j.gendis.2021.02.004

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Targeting m6A modification inhibits herpes virus 1 infectionPMID 35685469Read ↗

Co-option of mitochondrial nucleic acid sensing pathways by HSV-1 UL12.5 for reactivation from latent InfectionSemantic proximity Read ↗

RNA epitranscriptomics: Regulation of infection of RNA and DNA viruses by N 6 ‐methyladenosine (m 6 A)Semantic proximity Read ↗

MicroRNA Regulation of Human Herpesvirus LatencySemantic proximity Read ↗

Neuronal miR-138 represses HSV-2 lytic infection by regulating viral and host genes with mechanistic differences compared to HSV-1Semantic proximity Read ↗

RNA m6A methylation regulates virus–host interaction and EBNA2 expression during Epstein–Barr virus infectionSemantic proximity Read ↗

Neuronal miR-138 Represses HSV-2 Lytic Infection by Regulating Viral and Host Genes with Mechanistic Differences from HSV-1Semantic proximity Read ↗

N(6)-methyladenosine-binding protein YTHDF1 suppresses EBV replication and promotes EBV RNA decaySemantic proximity Read ↗

A Human Herpesvirus 6A-Encoded MicroRNA: Role in Viral Lytic ReplicationSemantic proximity Read ↗

Selective inhibition of microRNA processing by a herpesvirus-encoded microRNA triggers virus reactivation from latencySemantic proximity Read ↗

Mechanisms of HSV gene regulation during latency and reactivationSemantic proximity Read ↗

Herpes Simplex Virus 1 Deregulation of Host MicroRNAsSemantic proximity Read ↗

Herpesvirus latencySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.