Article
In vitro differentiation of human pancreatic duct-derived PANC-1 cells into β-cell phenotype using Tinospora cordifolia.
In vitro cellular & developmental biology. Animal - 1 May 2022
Damame Hemangee, Rooge Sheetalnath, Patil Rahul, Garad Chandramukhi, Arvindekar Akalpita
Abstract excerpt
Type 1 diabetes mellitus is an autoimmune disorder leading to loss of beta cells. There is a dire need to inhibit apoptosis and induce regeneration of new beta cells. There are plants in the Indian medicine system having the potential for rejuvenation. In the present study, we have attempted to evaluate the capacity of aqueous extract of Tinospora cordifolia to regenerate beta cells from PANC-1 ductal cells....
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