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Metabolic reprogramming in cancer and senescence

1 Mar 2025

Abstract excerpt

The rising trend in global cancer incidence has caused widespread concern, one of the main reasons being the aging of the global population. Statistical data show that cancer incidence and mortality rates show a clear upward trend with age. Although there is a commonality between dysregulated nutrient sensing, which is one of the main features of aging, and metabolic reprogramming of tumor cells, the specific...

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PMID: 40046406
DOI: 10.1002/mco2.70055

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