Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Single-Cell RNA-seq Analysis Reveals Cellular Functional Heterogeneity in Dermis Between Fibrotic and Regenerative Wound Healing Fates

17 May 2022

Abstract excerpt

Background: Fibrotic scars are common in both human and mouse skin wounds. However, wound-induced hair neogenesis in the murine wounding models often results in regenerative repair response. Herein, we aimed to uncover cellular functional heterogeneity in dermis between fibrotic and regenerative wound healing fates. Methods: The expression matrix of single-cell RNA sequencing (scRNA-seq) data of fibrotic and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Hair Growth and Disorders
Share to Mesenchymal stem cell research
Share to Wound Healing and Treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 35664010
DOI: 10.3389/fimmu.2022.875407

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Single-Cell RNA-seq Analysis Reveals Cellular Functional Heterogeneity in Dermis Between Fibrotic and Regenerative Wound Healing FatesPMID 35664010Read ↗

Single-cell RNA-seq reveals fibroblast heterogeneity and increased mesenchymal fibroblasts in human fibrotic skin diseasesSemantic proximity Read ↗

A consensus single-cell transcriptomic atlas of dermal fibroblast heterogeneitySemantic proximity Read ↗

Skin fibroblast functional heterogeneity in health and diseaseSemantic proximity Read ↗

Spatiotemporal single-cell roadmap of human skin wound healingSemantic proximity Read ↗

Decoding the molecular landscape of keloids: new insights from single-cell transcriptomicsSemantic proximity Read ↗

Profiling Fibrosis through Single-Cell and Spatial Transcriptomics Analysis: cell identity and tissue architectureSemantic proximity Read ↗

Spatiotemporal Single-Cell Roadmap of Human Skin Wound HealingSemantic proximity Read ↗

New insight into the role of fibroblasts in the epithelial immune microenvironment in the single-cell eraSemantic proximity Read ↗

Unraveling the role of CLOCK gene in fibrotic skin diseases: insights from single-cell RNA sequencing analysisSemantic proximity Read ↗

Fibroblast heterogeneity and functions: insights from single-cell sequencing in wound healing, breast cancer, ovarian cancer and melanomaSemantic proximity Read ↗

Shared and organ-specific gene expression programs of fibrotic diseasesSemantic proximity Read ↗

A single cell and spatial genomics atlas of human skin fibroblasts in health and diseaseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.