Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Sulfonylurea for improving neurological features in neonatal diabetes: A systematic review and meta-analyses.

Pediatric diabetes - 1 Sept 2022

de Gouveia Buff Passone Caroline, Giani Elisa, Vaivre-Douret Laurence, Kariyawasam Dulanjalee, Berdugo Marianne, Garcin Laure, Beltrand Jacques, Bernardo Wanderley Marques, Polak Michel

Abstract excerpt

OBJECTIVE: In monogenic diabetes due to KCNJ11 and ABCC8 mutations that impair KATP- channel function, sulfonylureas improve long-term glycemic control. Although KATP channels are extensively expressed in the brain, the effect of sulfonylureas on neurological function has varied widely. We evaluated published evidence about potential effects of sulfonylureas on neurological features, especially epilepsy,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Diabetes Mellitus
Share to Glyburide

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Infant, Newborn, Diseases

Share to KATP Channels

Share to Muscle Hypotonia

Share to Potassium Channels, Inwardly Rectifying

Share to Sulfonylurea Compounds

Share to Sulfonylurea Receptors

Source

Identifiers

PMID: 35657808
DOI: 10.1111/pedi.13376

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Sulfonylurea for improving neurological features in neonatal diabetes: A systematic review and meta-analyses.PMID 35657808Read ↗

Sulfonylurea Therapy Benefits Neurological and Psychomotor Functions in Patients With Neonatal Diabetes Owing to Potassium Channel Mutations.Semantic proximity Read ↗

Improved motor development and good long-term glycaemic control with sulfonylurea treatment in a patient with the syndrome of intermediate developmental delay, early-onset generalised epilepsy and neonatal diabetes associated with the V59M mutation in the KCNJ11 gene.Semantic proximity Read ↗

Long-term Follow-up of Glycemic and Neurological Outcomes in an International Series of Patients With Sulfonylurea-Treated ABCC8 Permanent Neonatal Diabetes.Semantic proximity Read ↗

Sulphonylurea therapy improves cognition in a patient with the V59M KCNJ11 mutation.Semantic proximity Read ↗

Neonatal diabetes due to potassium channel mutation: Response to sulfonylurea according to the genotype.Semantic proximity Read ↗

Neonatal diabetes with intractable epilepsy: DEND syndrome.Semantic proximity Read ↗

Sulfonylurea in the treatment of neonatal diabetes mellitus children with heterogeneous genetic backgrounds.Semantic proximity Read ↗

Neonatal Diabetes Caused by Activating Mutations in the Sulphonylurea ReceptorSemantic proximity Read ↗

Neonatal Diabetes and the KATP Channel: From Mutation to Therapy.Semantic proximity Read ↗

The G53D mutation in Kir6.2 (KCNJ11) is associated with neonatal diabetes and motor dysfunction in adulthood that is improved with sulfonylurea therapy.Semantic proximity Read ↗

A novel mutation causing DEND syndrome: a treatable channelopathy of pancreas and brain.Semantic proximity Read ↗

Visuomotor performance in KCNJ11-related neonatal diabetes is impaired in children with DEND-associated mutations and may be improved by early treatment with sulfonylureas.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.