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Article

Genetic therapeutic advancements for Dravet Syndrome.

Epilepsy & behavior : E&B - 1 Jul 2022

Chilcott Ellie, Díaz Juan Antinao, Bertram Cori, Berti Margherita, Karda Rajvinder

Abstract excerpt

Dravet Syndrome is a genetic epileptic syndrome characterized by severe and intractable seizures associated with cognitive, motor, and behavioral impairments. The disease is also linked with increased mortality mainly due to sudden unexpected death in epilepsy. Over 80% of cases are due to a de novo mutation in one allele of the SCN1A gene, which encodes the α-subunit of the voltage-gated ion channel NaV1.1....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 35653814
DOI: 10.1016/j.yebeh.2022.108741

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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