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Article

Genetic Association of VDR gene Apa1 and Taq1 Variants with Scleroderma in an Iranian Northeast Population.

Current rheumatology reviews - 1 Jan 2023

Mirfeizi Seyedeh Zahra, Nabizadeh-Marvast Majid, Jokar Mohammad-Hassan, Rafatpanah Houshang, Hashemzadeh Kamila, Mehrad-Majd Hassan

Abstract excerpt

BACKGROUND: Despite vigorous research efforts, the etiology of scleroderma (systemic sclerosis (SSc)) remains still unclear and both genetic and environmental factors clearly contribute to the pathogenesis of scleroderma. Reports of aberrant vitamin D status in scleroderma patients suggest a need for considering the genotype and allele frequencies of VDR gene polymorphisms. This case-control study aimed to...

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PMID: 35638543
DOI: 10.2174/2772432817666220530110524

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