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Acinetobacter baumannii response to cefiderocol challenge in human urine

24 May 2022

Abstract excerpt

Abstract Cefiderocol (CFDC) is a novel chlorocatechol-substituted siderophore antibiotic approved to treat complicated urinary tract infections (cUTI) and hospital-acquired and ventilator-acquired pneumonia (HAP/VAP). Previous work determined that albumin-rich human fluids increase the minimum inhibitory concentration (MICs) of Acinetobacter baumannii against CFDC and reduce the expression of genes related to...

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PMID: 35610334
DOI: 10.1038/s41598-022-12829-7

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