Article
Characterization of SARS-CoV-2 and host entry factors distribution in a COVID-19 autopsy series
23 Aug 2021
Abstract excerpt
Abstract Background SARS-CoV-2 is a highly contagious virus that causes the disease COVID-19. We have recently reported that androgens regulate the expression of SARS-CoV-2 host entry factors ACE2 and TMPRSS2, and androgen receptor (AR) in lung epithelial cells. We also demonstrated that the transcriptional repression of the AR enhanceosome inhibited SARS-CoV-2 infection in vitro. Methods To better understand the...
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