Article
Machine learning phenomics (MLP) combining deep learning with time-lapse-microscopy for monitoring colorectal adenocarcinoma cells gene expression and drug-response.
Scientific reports - 20 May 2022
D'Orazio M, Murdocca M, Mencattini A, Casti P, Filippi J, Antonelli G, Di Giuseppe D, Comes M C, Di Natale C, Sangiuolo F, Martinelli E
Abstract excerpt
High-throughput phenotyping is becoming increasingly available thanks to analytical and bioinformatics approaches that enable the use of very high-dimensional data and to the availability of dynamic models that link phenomena across levels: from genes to cells, from cells to organs, and through the whole organism. The combination of phenomics, deep learning, and machine learning represents a strong potential for...
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