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Genome-wide association studies in Japanese women identified genetic loci associated with wrinkles and sagging.

Experimental dermatology - 1 Sept 2022

Okuno Ryosuke, Inoue Yu, Hasebe Yuichi, Igarashi Toshio, Kawagishi-Hotta Mika, Yamada Takaaki, Hasegawa Seiji

Abstract excerpt

Wrinkles and sagging are caused by various factors, such as ultraviolet rays; however, recent findings demonstrated that some individuals are genetically predisposed to these phenotypes of skin aging. The contribution of single nucleotide polymorphisms (SNPs) to the development of wrinkles and sagging has been demonstrated in genome-wide association studies (GWAS). However, these findings were mainly obtained...

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PMID: 35587111
DOI: 10.1111/exd.14612

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