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Article

Detection of MET amplification by droplet digital PCR in peripheral blood samples of non-small cell lung cancer.

Journal of cancer research and clinical oncology - 1 May 2023

Fan Ying, Sun Rui, Wang Zhizhong, Zhang Yuying, Xiao Xiao, Liu Yizhe, Xin Beibei, Xiong Hui, Lu Daru, Ma Jie

Abstract excerpt

PURPOSE: Mesenchymal-epithelial transition (MET) amplification is one of the mechanisms accounting for the resistance of epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) in lung cancer patients, as well as the poor prognosis. Fluorescence in situ hybridization (FISH) is the most widely used method for MET amplification detection. However, it is inapplicable when tissue samples were...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 35583827
DOI: 10.1007/s00432-022-04048-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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