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Article

Depressive Symptoms Partially Mediate the Association of Frailty Phenotype Symptoms and Cognition for Females but Not Males.

Journal of aging and health - 1 Jan 2023

Resciniti Nicholas V, Farina Mateo P, Merchant Anwar T, Lohman Matthew C

Abstract excerpt

OBJECTIVES: We aimed to evaluate whether depressive symptoms mediated the relationship between frailty phenotype and cognitive function by sex. METHODS: Data came from the Health and Retirement Study from 2012-2016. The outcome was measured by Fried's frailty criteria, our outcome was continuous global cognition, and mediator was depressive symptoms. We used mediation analysis, stratified by sex, to estimate the...

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Identifiers

PMID: 35527693
DOI: 10.1177/08982643221100688
PMCID: PMC9640765

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